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KMID : 0383820100690040243
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Tuberculosis and Respiratory Diseases
2010 Volume.69 No. 4 p.243 ~ p.249
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Risk Factors Associated with Frequent Hospital Readmissions for Exacerbation of COPD
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Kim Mi-Hyun
Lee Kwang-Ha
Kim Ki-Uk
Park Hye-Kyung
JEon Doo-Soo
Kim Yun-Seong
Lee Min-Ki
Park Soon-Kew
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Abstract
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Background Chronic obstructive pulmonary disease (COPD) is one of the leading causes of disability and mortality worldwide. The aim of this study was to evaluate the risk factors associated with recurrent hospital admissions for exacerbation of COPD in Korea.
Methods A retrospective study of 77 consecutive patients hospitalized for exacerbation of COPD at Pusan National University Hospital during the time period January 2005 to May 2008 was performed. The information was collected from the hospitalization period: clinical information, spirometric measures, and laboratory variables. In addition, socioeconomic characteristics, co-morbidity, anxiety, and depression were reviewed. Frequent readmission was defined as 2 or more hospitalizations in the year following discharge.
Results During the 1-year period after discharge, 42 patients (54.6%) reported one hospital admission and 35 patients (45.4%) reported 2 or more hospital readmissions. Among the 35 frequent readmission patients, 4 had more than 10 readmissions. Univariate analysis showed that a body mass index (BMI) <18.5 kg/m2, duration >36 months, forced expiratory volume in 1 second (FEV1) <50% predicted, arterial CO2 partial pressure (PaCO2) >40 mm Hg, and arterial oxygen saturation (SaO2) <95% at discharge were associated significantly with frequent readmissions. The multivariate analysis revealed that BMI <18.5 kg/m2, PaCO2 >40 mm Hg at discharge were independently associated with frequent readmissions for exacerbation of COPD.
Conclusion Frequent readmissions for exacerbation of COPD were associated with low BMI and hypercapnia at discharge.
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KEYWORD
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Pulmonary Disease, Chronic Obstructive, Exacerbation, Patient Readmission, Body Mass Index, Hypercapnia
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